Effects of Simulated Preparations of Plants used in Nigerian Traditional Medicine on <i>Candida</i> spp. Associated with Vaginal Candidiasis

Authors

  • Adenike Adedayo Ogunshe University of Ibadan, Nigeria
  • Oladipupo A Lawal Department of Chemistry, University of Zululand,
  • Chinedum I Iheakanwa University of Ibadan

Keywords:

Antimicrobial, Medicinal plants, STI, Candida, Candidiasis, Lactobacillus

Abstract

Some Nigerian medicinal plants are popular among traditional producers of phytotherapies in the treatment of sexually related infections. For this study we used modified agar disk, agar spot and agar well-diffusion methods, preparations of simulated crude aqueous and ethanolic extracts of 11 traditionally used medicinal plants for in vitro antimicrobial activities against seventy five strains of Candida species associated with Candida vaginitis and 37 vaginal Lactobacillus species. Candida pseudotropicalis (Castell.) Basgal were minimally inhibited by the plant extracts, while the rate of inhibition of other Candida strains by the ethanolic extracts of the plants were, Ageratum conyzoides L. (44.4 - 66.7%), Anthocleista djalonensis A. Chev. (57.1 - 66.7%), Senna alata (L.) Roxb. (44.4 - 75.0%) Ficus exasperata Vahl. (44.4 - 62.5%), Gliricidia sepium Kunth ex Steud. (64.3%-75.0%) Chromolaena odorata (L.) R.M. King & H. Rob.(57.1%-62.5%) and Rauwolfia vomitoria Afzel. (62.5%). Apart from Aspilia africana (Pers.) C.D. Adams (24.3%) and Ageratum conyzoides L. (35.1%), very low in vitro inhibitory activities of between 5.4% and 16.2% were produced by the medicinal plants against the vaginal Lactobacillus species indicating their ethnophytotherapeutic safety.

Author Biographies

Adenike Adedayo Ogunshe, University of Ibadan, Nigeria

LECTURER APPLIED MICROBIOLOGY & INFECTIOUS DISEASES UNIT, DEPARTMENT OF BOTANY & MICROBIOLOGY, UNIVERSITY OF IBADAN, NIGERIA

Oladipupo A Lawal, Department of Chemistry, University of Zululand,

Lecturer, Department of Chemistry Lagos State University, Ojoo, Lagos, Nigeria Research Fellow, University of Zululand, South Africa/ Lecturer, Department of Chemistry, Lagos State University, Lagos, Nigeria

Chinedum I Iheakanwa, University of Ibadan

Technologist, Faculty of Veterinary Medicine, University of Ibadan, Nigeria

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Published

2008-12-05

How to Cite

Ogunshe, A. A., Lawal, O. A., & Iheakanwa, C. I. (2008). Effects of Simulated Preparations of Plants used in Nigerian Traditional Medicine on &lt;i&gt;Candida&lt;/i&gt; spp. Associated with Vaginal Candidiasis. Ethnobotany Research and Applications, 6, 373–383. Retrieved from https://ethnobotanyjournal.org/index.php/era/article/view/165

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Section

Research